Cargando…

Structures of Lysenin Reveal a Shared Evolutionary Origin for Pore-Forming Proteins And Its Mode of Sphingomyelin Recognition

Pore-forming proteins insert from solution into membranes to create lesions, undergoing a structural rearrangement often accompanied by oligomerization. Lysenin, a pore-forming toxin from the earthworm Eisenia fetida, specifically interacts with sphingomyelin (SM) and may confer innate immunity agai...

Descripción completa

Detalles Bibliográficos
Autores principales:	De Colibus, Luigi, Sonnen, Andreas F.-P., Morris, Keith J., Siebert, C. Alistair, Abrusci, Patrizia, Plitzko, Jürgen, Hodnik, Vesna, Leippe, Matthias, Volpi, Emanuela, Anderluh, Gregor, Gilbert, Robert J.C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526787/ https://www.ncbi.nlm.nih.gov/pubmed/22819216 http://dx.doi.org/10.1016/j.str.2012.06.011

Ejemplares similares

Insights into the Voltage Regulation Mechanism of the Pore-Forming Toxin Lysenin
por: Bryant, Sheenah Lynn, et al.
Publicado: (2018)

Temporary Membrane Permeabilization via the Pore-Forming Toxin Lysenin
por: Shrestha, Nisha, et al.
Publicado: (2020)

Tracking Cholesterol/Sphingomyelin-Rich Membrane Domains with the Ostreolysin A-mCherry Protein
por: Skočaj, Matej, et al.
Publicado: (2014)

Earthworm-Derived Pore-Forming Toxin Lysenin and Screening of Its Inhibitors
por: Sukumwang, Neelanun, et al.
Publicado: (2013)

Toxin Detection by Surface Plasmon Resonance
por: Hodnik, Vesna, et al.
Publicado: (2009)

Cryo-EM structure of lysenin pore elucidates membrane insertion by an aerolysin family protein
por: Bokori-Brown, Monika, et al.
Publicado: (2016)

Incomplete pneumolysin oligomers form membrane pores
por: Sonnen, Andreas F.-P., et al.
Publicado: (2014)

Lysenin Channels as Sensors for Ions and Molecules
por: Bogard, Andrew, et al.
Publicado: (2020)

(19)F NMR studies provide insights into lipid membrane interactions of listeriolysin O, a pore forming toxin from Listeria monocytogenes
por: Kozorog, Mirijam, et al.
Publicado: (2018)

Insight into the Structural Dynamics of the Lysenin During Prepore-to-Pore Transition Using Hydrogen–Deuterium Exchange Mass Spectrometry
por: Kulma, Magdalena, et al.
Publicado: (2019)

Cationic Polymers Inhibit the Conductance of Lysenin Channels
por: Fologea, Daniel, et al.
Publicado: (2013)

Stochastic sensing of Angiotensin II with lysenin channels
por: Shrestha, Nisha, et al.
Publicado: (2017)

The Ionic Selectivity of Lysenin Channels in Open and Sub-Conducting States
por: Bogard, Andrew, et al.
Publicado: (2021)

Liposomes Prevent In Vitro Hemolysis Induced by Streptolysin O and Lysenin
por: Ayllon, Marcelo, et al.
Publicado: (2021)

Inhibition of Pore-Forming Proteins
por: Omersa, Neža, et al.
Publicado: (2019)

An Effective Electric Dipole Model for Voltage-induced Gating Mechanism of Lysenin
por: Faouri, Radwan Al, et al.
Publicado: (2019)

Modulation of Voltage-Gating and Hysteresis of Lysenin Channels by Cu(2+) Ions
por: Bogard, Andrew, et al.
Publicado: (2023)

Crystal structures of cholera toxin in complex with fucosylated receptors point to importance of secondary binding site
por: Heim, Joel B., et al.
Publicado: (2019)

Specificity of Escherichia coli Heat-Labile Enterotoxin Investigated by Single-Site Mutagenesis and Crystallography
por: Heggelund, Julie Elisabeth, et al.
Publicado: (2019)

Bacteriophage GIL01 gp7 interacts with host LexA repressor to enhance DNA binding and inhibit RecA-mediated auto-cleavage
por: Fornelos, Nadine, et al.
Publicado: (2015)

ZnO nanoparticles modulate the ionic transport and voltage regulation of lysenin nanochannels
por: Bryant, Sheenah L., et al.
Publicado: (2017)

High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence
por: Heggelund, Julie Elisabeth, et al.
Publicado: (2016)

Significance of K(L/V)WX(I/L/V)P Epitope of the B2Gpi in Its (Patho)Physiologic Function
por: Žager, Urška, et al.
Publicado: (2011)

Single channel properties of lysenin measured in artificial lipid bilayers and their applications to biomolecule detection
por: AOKI, Takaaki, et al.
Publicado: (2010)

Pore formation by human stefin B in its native and oligomeric states and the consequent amyloid induced toxicity
por: Anderluh, Gregor, et al.
Publicado: (2012)

ON THE COMPONENTS OF SPHINGOMYELIN
por: Levene, P. A.
Publicado: (1913)

Role of Pore-Forming Toxins in Neonatal Sepsis
por: Sonnen, Andreas F.-P., et al.
Publicado: (2013)

Raft-based sphingomyelin interactions revealed by new fluorescent sphingomyelin analogs
por: Kinoshita, Masanao, et al.
Publicado: (2017)

The LexA regulated genes of the Clostridium difficile
por: Walter, Beata M, et al.
Publicado: (2014)

Molecular basis for functional diversity among microbial Nep1-like proteins
por: Lenarčič, Tea, et al.
Publicado: (2019)

Measuring kinetic drivers of pneumolysin pore structure
por: Gilbert, Robert J. C., et al.
Publicado: (2016)

Structural insight into LexA–RecA* interaction
por: Kovačič, Lidija, et al.
Publicado: (2013)

Archaeal aminoacyl-tRNA synthetases interact with the ribosome to recycle tRNAs
por: Godinic-Mikulcic, Vlatka, et al.
Publicado: (2014)

Development of Recombinant Lactococcus lactis Displaying Albumin-Binding Domain Variants against Shiga Toxin 1 B Subunit
por: Zadravec, Petra, et al.
Publicado: (2016)

Ceramide/Sphingomyelin Rheostat Regulated by Sphingomyelin Synthases and Chronic Diseases in Murine Models
por: Taniguchi, Makoto, et al.
Publicado: (2020)

Sphingomyelin generated by sphingomyelin synthase 1 is involved in attachment and infection with Japanese encephalitis virus
por: Taniguchi, Makoto, et al.
Publicado: (2016)

Sphingomyelins and ent-Sphingomyelins Form Homophilic Nano-Subdomains within Liquid Ordered Domains
por: Yano, Yo, et al.
Publicado: (2020)

Sphingomyelin is the master of its domain
por: Short, Ben
Publicado: (2014)

Nuclear sphingomyelin in neurodegenerative diseases
por: Albi, Elisabetta, et al.
Publicado: (2021)

Emphatic visualization of sphingomyelin-rich domains by inter-lipid FRET imaging using fluorescent sphingomyelins
por: Kinoshita, Masanao, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_qsl02uh7cs6obj7if8r6fmhi8k