MOLECULAR DETERMINANTS OF SELECTIVE CLEARANCE OF PROTEIN INCLUSIONS BY AUTOPHAGY

Protein quality control is essential for cellular survival. Failure to eliminate pathogenic proteins leads to their intracellular accumulation in the form of protein aggregates. Autophagy can recognize protein aggregates and degrade them in lysosomes. However, some aggregates escape the autophagic s...

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Detalles Bibliográficos
Autores principales: Wong, Esther, Bejarano, Eloy, Rakshit, Moumita, Lee, Karen, Hanson, Hugo H., Zaarur, Nava, Phillips, Greg R., Sherman, Michael Y., Cuervo, Ana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526956/
https://www.ncbi.nlm.nih.gov/pubmed/23212369
http://dx.doi.org/10.1038/ncomms2244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526956/
https://www.ncbi.nlm.nih.gov/pubmed/23212369
http://dx.doi.org/10.1038/ncomms2244

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