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Concerted epigenetic signatures inheritance at PcG targets through replication

Polycomb group of proteins (PcG), by controlling gene silencing transcriptional programs through cell cycle, lock cell identity and memory. Recent chromatin genome-wide studies indicate that PcG targets sites are bivalent domains with overlapping repressive H3K27me3 and active H3K4me3 mark domains....

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Detalles Bibliográficos
Autores principales: Lanzuolo, Chiara, Lo Sardo, Federica, Orlando, Valerio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527071/
https://www.ncbi.nlm.nih.gov/pubmed/22421150
http://dx.doi.org/10.4161/cc.19710