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The relationship between the hierarchical position of proteins in the human signal transduction network and their rate of evolution
BACKGROUND: Proteins evolve at disparate rates, as a result of the action of different types and strengths of evolutionary forces. An open question in evolutionary biology is what factors are responsible for this variability. In general, proteins whose function has a great impact on organisms’ fitne...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527147/ https://www.ncbi.nlm.nih.gov/pubmed/23020283 http://dx.doi.org/10.1186/1471-2148-12-192 |