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Structural insights from random mutagenesis of Campylobacter jejuni oligosaccharyltransferase PglB

BACKGROUND: Protein glycosylation is of fundamental importance in many biological systems. The discovery of N-glycosylation in bacteria and the functional expression of the N-oligosaccharyltransferase PglB of Campylobacter jejuni in Escherichia coli enabled the production of engineered glycoproteins...

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Detalles Bibliográficos
Autores principales: Ihssen, Julian, Kowarik, Michael, Wiesli, Luzia, Reiss, Renate, Wacker, Michael, Thöny-Meyer, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527161/
https://www.ncbi.nlm.nih.gov/pubmed/23006740
http://dx.doi.org/10.1186/1472-6750-12-67