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Ku80 is highly expressed in lung adenocarcinoma and promotes cisplatin resistance

BACKGROUND: Ku80 is crucially implicated in DNA repair, apoptosis, and chemoresistance. In this study, we aimed to assess the expression of Ku80 in clinical lung adenocarcinoma specimens, and investigate its role in the regulation of cisplatin sensitivity in cisplatin resistant human lung adenocarci...

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Detalles Bibliográficos
Autores principales: Ma, Qingshan, Li, Ping, Xu, Minyu, Yin, Jinzhi, Su, Zhenzhong, Li, Wei, Zhang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527197/
https://www.ncbi.nlm.nih.gov/pubmed/23181744
http://dx.doi.org/10.1186/1756-9966-31-99