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Inhibition of uncoupling protein 2 with genipin exacerbates palmitate-induced hepatic steatosis

BACKGROUND: Uncoupling protein 2 (UCP2) was reported to be involved in lipid metabolism through regulating the production of superoxide anion. However, the role of UCP2 in hepatocytes steatosis has not been determined. We hypothesized that UCP2 might regulate hepatic steatosis via suppressing oxidat...

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Detalles Bibliográficos
Autores principales: Ma, Shuangtao, Yang, Dachun, Li, De, Tan, Yan, Tang, Bing, Yang, Yongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527221/
https://www.ncbi.nlm.nih.gov/pubmed/23151243
http://dx.doi.org/10.1186/1476-511X-11-154