Modeling coding-sequence evolution within the context of residue solvent accessibility

BACKGROUND: Protein structure mediates site-specific patterns of sequence divergence. In particular, residues in the core of a protein (solvent-inaccessible residues) tend to be more evolutionarily conserved than residues on the surface (solvent-accessible residues). RESULTS: Here, we present a mode...

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Detalles Bibliográficos
Autores principales: Scherrer, Michael P, Meyer, Austin G, Wilke, Claus O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527230/
https://www.ncbi.nlm.nih.gov/pubmed/22967129
http://dx.doi.org/10.1186/1471-2148-12-179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527230/
https://www.ncbi.nlm.nih.gov/pubmed/22967129
http://dx.doi.org/10.1186/1471-2148-12-179

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