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Identifying targets of multiple co-regulating transcription factors from expression time-series by Bayesian model comparison

BACKGROUND: Complete transcriptional regulatory network inference is a huge challenge because of the complexity of the network and sparsity of available data. One approach to make it more manageable is to focus on the inference of context-specific networks involving a few interacting transcription f...

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Detalles Bibliográficos
Autores principales: Titsias, Michalis K, Honkela, Antti, Lawrence, Neil D, Rattray, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527261/
https://www.ncbi.nlm.nih.gov/pubmed/22647244
http://dx.doi.org/10.1186/1752-0509-6-53