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Novel Modeling of Combinatorial miRNA Targeting Identifies SNP with Potential Role in Bone Density

MicroRNAs (miRNAs) are post-transcriptional regulators that bind to their target mRNAs through base complementarity. Predicting miRNA targets is a challenging task and various studies showed that existing algorithms suffer from high number of false predictions and low to moderate overlap in their pr...

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Detalles Bibliográficos
Autores principales: Coronnello, Claudia, Hartmaier, Ryan, Arora, Arshi, Huleihel, Luai, Pandit, Kusum V., Bais, Abha S., Butterworth, Michael, Kaminski, Naftali, Stormo, Gary D., Oesterreich, Steffi, Benos, Panayiotis V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527281/
https://www.ncbi.nlm.nih.gov/pubmed/23284279
http://dx.doi.org/10.1371/journal.pcbi.1002830