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Keratin 8 variants are infrequent in patients with alcohol-related liver cirrhosis and do not associate with development of hepatocellular carcinoma

BACKGROUND: Keratins 8/18 (K8/K18) are established hepatoprotective proteins and K8/K18 variants predispose to development and adverse outcome of multiple liver disorders. The importance of K8/K18 in alcoholic liver disease as well as in established cirrhosis remains unknown. METHODS: We analyzed th...

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Detalles Bibliográficos
Autores principales: Usachov, Valentyn, Nahon, Pierre, Lunova, Mariia, Ziol, Marianne, Rufat, Pierre, Sutton, Angela, Beaugrand, Michel, Strnad, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527286/
https://www.ncbi.nlm.nih.gov/pubmed/23078008
http://dx.doi.org/10.1186/1471-230X-12-147