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Nucleoid-Associated Proteins Affect Mutation Dynamics in E. coli in a Growth Phase-Specific Manner

The binding of proteins can shield DNA from mutagenic processes but also interfere with efficient repair. How the presence of DNA-binding proteins shapes intra-genomic differences in mutability and, ultimately, sequence variation in natural populations, however, remains poorly understood. In this st...

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Detalles Bibliográficos
Autores principales: Warnecke, Tobias, Supek, Fran, Lehner, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527292/
https://www.ncbi.nlm.nih.gov/pubmed/23284284
http://dx.doi.org/10.1371/journal.pcbi.1002846