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Protein stickiness, rather than number of functional protein-protein interactions, predicts expression noise and plasticity in yeast
BACKGROUND: A hub protein is one that interacts with many functional partners. The annotation of hub proteins, or more generally the protein-protein interaction “degree” of each gene, requires quality genome-wide data. Data obtained using yeast two-hybrid methods contain many false positive interact...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527306/ https://www.ncbi.nlm.nih.gov/pubmed/23017156 http://dx.doi.org/10.1186/1752-0509-6-128 |