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Protein stickiness, rather than number of functional protein-protein interactions, predicts expression noise and plasticity in yeast

BACKGROUND: A hub protein is one that interacts with many functional partners. The annotation of hub proteins, or more generally the protein-protein interaction “degree” of each gene, requires quality genome-wide data. Data obtained using yeast two-hybrid methods contain many false positive interact...

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Detalles Bibliográficos
Autores principales:	Brettner, Leandra M, Masel, Joanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527306/ https://www.ncbi.nlm.nih.gov/pubmed/23017156 http://dx.doi.org/10.1186/1752-0509-6-128

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