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The role of the cofilin-actin rod stress response in neurodegenerative diseases uncovers potential new drug targets
The cofilin-actin rod stress response is an actin cytoskeletal dynamic arrest that occurs in cells under a variety of stress conditions. Upon stress, the rapidly activated cofilin saturates actin filaments causing them to bundle into rod structures in either the nucleus or cytoplasm, halting actin p...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527314/ https://www.ncbi.nlm.nih.gov/pubmed/23267414 http://dx.doi.org/10.4161/bioa.22549 |