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The role of the cofilin-actin rod stress response in neurodegenerative diseases uncovers potential new drug targets

The cofilin-actin rod stress response is an actin cytoskeletal dynamic arrest that occurs in cells under a variety of stress conditions. Upon stress, the rapidly activated cofilin saturates actin filaments causing them to bundle into rod structures in either the nucleus or cytoplasm, halting actin p...

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Detalles Bibliográficos
Autores principales: Munsie, Lise N., Truant, Ray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527314/
https://www.ncbi.nlm.nih.gov/pubmed/23267414
http://dx.doi.org/10.4161/bioa.22549

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