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Erythropoietin attenuates cardiac dysfunction by increasing myocardial angiogenesis and inhibiting interstitial fibrosis in diabetic rats

BACKGROUND: Recent studies revealed that erythropoietin (EPO) has tissue-protective effects in the heart by increasing vascular endothelial growth factor (VEGF) expression and attenuating myocardial fibrosis in ischemia models. In this study, we investigated the effect of EPO on ventricular remodeli...

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Detalles Bibliográficos
Autores principales: Lu, Jing, Yao, Yu-yu, Dai, Qi-ming, Ma, Gen-shan, Zhang, Shu-feng, Cao, Lei, Ren, Li-qun, Liu, Nai-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527329/
https://www.ncbi.nlm.nih.gov/pubmed/22954171
http://dx.doi.org/10.1186/1475-2840-11-105