Cargando…

Hypothesis Testing and Power Calculations for Taxonomic-Based Human Microbiome Data

This paper presents new biostatistical methods for the analysis of microbiome data based on a fully parametric approach using all the data. The Dirichlet-multinomial distribution allows the analyst to calculate power and sample sizes for experimental design, perform tests of hypotheses (e.g., compar...

Descripción completa

Detalles Bibliográficos
Autores principales: La Rosa, Patricio S., Brooks, J. Paul, Deych, Elena, Boone, Edward L., Edwards, David J., Wang, Qin, Sodergren, Erica, Weinstock, George, Shannon, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527355/
https://www.ncbi.nlm.nih.gov/pubmed/23284876
http://dx.doi.org/10.1371/journal.pone.0052078