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Hypothesis Testing and Power Calculations for Taxonomic-Based Human Microbiome Data

This paper presents new biostatistical methods for the analysis of microbiome data based on a fully parametric approach using all the data. The Dirichlet-multinomial distribution allows the analyst to calculate power and sample sizes for experimental design, perform tests of hypotheses (e.g., compar...

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Detalles Bibliográficos
Autores principales:	La Rosa, Patricio S., Brooks, J. Paul, Deych, Elena, Boone, Edward L., Edwards, David J., Wang, Qin, Sodergren, Erica, Weinstock, George, Shannon, William D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527355/ https://www.ncbi.nlm.nih.gov/pubmed/23284876 http://dx.doi.org/10.1371/journal.pone.0052078

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