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Characterization of Drosophila GDNF Receptor-Like and Evidence for Its Evolutionarily Conserved Interaction with Neural Cell Adhesion Molecule (NCAM)/FasII

BACKGROUND: Glial cell line-derived neurotrophic factor (GDNF) family ligands are secreted growth factors distantly related to the TGF-β superfamily. In mammals, they bind to the GDNF family receptor α (Gfrα) and signal through the Ret receptor tyrosine kinase. In order to gain insight into the evol...

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Detalles Bibliográficos
Autores principales: Kallijärvi, Jukka, Stratoulias, Vassilis, Virtanen, Kristel, Hietakangas, Ville, Heino, Tapio I., Saarma, Mart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527400/
https://www.ncbi.nlm.nih.gov/pubmed/23284846
http://dx.doi.org/10.1371/journal.pone.0051997