Characterization of Shear-Sensitive Genes in the Normal Rat Aorta Identifies Hand2 as a Major Flow-Responsive Transcription Factor

OBJECTIVE: Shear forces play a key role in the maintenance of vessel wall integrity. Current understanding regarding shear-dependent gene expression is mainly based on in vitro or in vivo observations with experimentally deranged shear, hence reflecting acute molecular events in relation to flow. Ou...

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Detalles Bibliográficos
Autores principales: Björck, Hanna M., Renner, Johan, Maleki, Shohreh, Nilsson, Siv F. E., Kihlberg, Johan, Folkersen, Lasse, Karlsson, Matts, Ebbers, Tino, Eriksson, Per, Länne, Toste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527404/
https://www.ncbi.nlm.nih.gov/pubmed/23284944
http://dx.doi.org/10.1371/journal.pone.0052227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527404/
https://www.ncbi.nlm.nih.gov/pubmed/23284944
http://dx.doi.org/10.1371/journal.pone.0052227

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