Influence of the Internalization Pathway on the Efficacy of siRNA Delivery by Cationic Fluorescent Nanodiamonds in the Ewing Sarcoma Cell Model

Small interfering RNAs (siRNAs) are powerful tools commonly used for the specific inhibition of gene expression. However, vectorization is required to facilitate cell penetration and to prevent siRNA degradation by nucleases. We have shown that diamond nanocrystals coated with cationic polymer can b...

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Detalles Bibliográficos
Autores principales: Alhaddad, Anna, Durieu, Catherine, Dantelle, Géraldine, Le Cam, Eric, Malvy, Claude, Treussart, François, Bertrand, Jean-Rémi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527409/
https://www.ncbi.nlm.nih.gov/pubmed/23284935
http://dx.doi.org/10.1371/journal.pone.0052207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527409/
https://www.ncbi.nlm.nih.gov/pubmed/23284935
http://dx.doi.org/10.1371/journal.pone.0052207

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