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Intramyocardial Delivery of Mesenchymal Stem Cell-Seeded Hydrogel Preserves Cardiac Function and Attenuates Ventricular Remodeling after Myocardial Infarction

BACKGROUND: To improve the efficacy of bone marrow-derived mesenchymal stem cell (MSC) therapy targeted to infarcted myocardium, we investigated whether a self-setting silanized hydroxypropyl methylcellulose (Si-HPMC) hydrogel seeded with MSC (MSC+hydrogel) could preserve cardiac function and attenu...

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Detalles Bibliográficos
Autores principales: Mathieu, Eva, Lamirault, Guillaume, Toquet, Claire, Lhommet, Pierre, Rederstorff, Emilie, Sourice, Sophie, Biteau, Kevin, Hulin, Philippe, Forest, Virginie, Weiss, Pierre, Guicheux, Jérôme, Lemarchand, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527411/
https://www.ncbi.nlm.nih.gov/pubmed/23284842
http://dx.doi.org/10.1371/journal.pone.0051991