Nippostrongylus-Induced Intestinal Hypercontractility Requires IL-4 Receptor Alpha-Responsiveness by T Cells in Mice

Gut-dwelling helminthes induce potent IL-4 and IL-13 dominated type 2 T helper cell (T(H)2) immune responses, with IL-13 production being essential for Nippostrongylus brasiliensis expulsion. This T(H)2 response results in intestinal inflammation associated with local infiltration by T cells and mac...

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Detalles Bibliográficos
Autores principales: Schmidt, Saskia, Hoving, J. Claire, Horsnell, William G. C., Mearns, Helen, Cutler, Antony J., Brombacher, Tiroyaone M., Brombacher, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527412/
https://www.ncbi.nlm.nih.gov/pubmed/23284939
http://dx.doi.org/10.1371/journal.pone.0052211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527412/
https://www.ncbi.nlm.nih.gov/pubmed/23284939
http://dx.doi.org/10.1371/journal.pone.0052211

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