Total Synthesis of Septocylindrin B and C-Terminus Modified Analogues

The total synthesis is reported of the peptaibol Septocylindrin B which is related to the well documented channel forming peptaibol antibiotic Alamethicin. Several analogues were synthesized with a modified C-terminus, to investigate the SAR of the terminal residue Phaol. All these peptides were tes...

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Detalles Bibliográficos
Autores principales: Nelissen, Jo, Nuyts, Koen, De Zotti, Marta, Lavigne, Rob, Lamberigts, Chris, De Borggraeve, Wim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527430/
https://www.ncbi.nlm.nih.gov/pubmed/23284749
http://dx.doi.org/10.1371/journal.pone.0051708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527430/
https://www.ncbi.nlm.nih.gov/pubmed/23284749
http://dx.doi.org/10.1371/journal.pone.0051708

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