Roles for NHERF1 and NHERF2 on the Regulation of C3a Receptor Signaling in Human Mast Cells

BACKGROUND: The anaphylatoxin C3a binds to the G protein coupled receptor (GPCR, C3aR) and activates divergent signaling pathways to induce degranulation and cytokine production in human mast cells. Adapter proteins such as the Na(+)/H(+) exchange regulatory factor (NHERF1 and NHERF2) have been impl...

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Detalles Bibliográficos
Autores principales: Subramanian, Hariharan, Gupta, Kshitij, Ali, Hydar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527443/
https://www.ncbi.nlm.nih.gov/pubmed/23284683
http://dx.doi.org/10.1371/journal.pone.0051355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527443/
https://www.ncbi.nlm.nih.gov/pubmed/23284683
http://dx.doi.org/10.1371/journal.pone.0051355

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