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PGJ(2) Provides Prolonged CNS Stroke Protection by Reducing White Matter Edema

Few clinically effective approaches reduce CNS-white matter injury. After early in-vivo white matter infarct, NFκB-driven pro-inflammatory signals can amplify a relatively small amount of vascular damage, resulting in progressive endothelial dysfunction to create a severe ischemic lesion. This proce...

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Detalles Bibliográficos
Autores principales: Nicholson, James D., Puche, Adam C., Guo, Yan, Weinreich, Daniel, Slater, Bernard J., Bernstein, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527449/
https://www.ncbi.nlm.nih.gov/pubmed/23284631
http://dx.doi.org/10.1371/journal.pone.0050021