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PGJ(2) Provides Prolonged CNS Stroke Protection by Reducing White Matter Edema
Few clinically effective approaches reduce CNS-white matter injury. After early in-vivo white matter infarct, NFκB-driven pro-inflammatory signals can amplify a relatively small amount of vascular damage, resulting in progressive endothelial dysfunction to create a severe ischemic lesion. This proce...
Autores principales: | Nicholson, James D., Puche, Adam C., Guo, Yan, Weinreich, Daniel, Slater, Bernard J., Bernstein, Steven L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527449/ https://www.ncbi.nlm.nih.gov/pubmed/23284631 http://dx.doi.org/10.1371/journal.pone.0050021 |
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