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MELOE-1 Antigen Contains Multiple HLA Class II T Cell Epitopes Recognized by Th1 CD4+ T Cells from Melanoma Patients

MELOE-1 is an overexpressed melanoma antigen containing a HLA-A2 restricted epitope, involved in melanoma immunosurveillance of patients adoptively transferred with tumour infiltrating lymphocytes (TIL). The use of the full-length antigen (46 aa) for anti-melanoma vaccination could be considered, su...

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Detalles Bibliográficos
Autores principales: Bobinet, Mathilde, Vignard, Virginie, Rogel, Anne, Khammari, Amir, Dreno, Brigitte, Lang, Francois, Labarriere, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527452/
https://www.ncbi.nlm.nih.gov/pubmed/23284752
http://dx.doi.org/10.1371/journal.pone.0051716