The Adjuvant Double Mutant Escherichia coli Heat Labile Toxin Enhances IL-17A Production in Human T Cells Specific for Bacterial Vaccine Antigens

The strong adjuvant activity and low enterotoxicity of the novel mucosal adjuvant double mutant Escherichia coli heat labile toxin, LT(R192G/L211A) or dmLT, demonstrated in mice, makes this molecule a promising adjuvant candidate. However, little is known about the mechanisms responsible for the adj...

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Detalles Bibliográficos
Autores principales: Leach, Susannah, Clements, John D., Kaim, Joanna, Lundgren, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527457/
https://www.ncbi.nlm.nih.gov/pubmed/23284753
http://dx.doi.org/10.1371/journal.pone.0051718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527457/
https://www.ncbi.nlm.nih.gov/pubmed/23284753
http://dx.doi.org/10.1371/journal.pone.0051718

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