Comprehensive Behavioral and Molecular Characterization of a New Knock-In Mouse Model of Huntington’s Disease: zQ175

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor, cognitive and psychiatric manifestations. Since the mutation responsible for the disease was identified as an unstable expansion of CAG repeats in the gene encoding the huntingtin protein in 1993, n...

Descripción completa

Detalles Bibliográficos
Autores principales: Menalled, Liliana B., Kudwa, Andrea E., Miller, Sam, Fitzpatrick, Jon, Watson-Johnson, Judy, Keating, Nicole, Ruiz, Melinda, Mushlin, Richard, Alosio, William, McConnell, Kristi, Connor, David, Murphy, Carol, Oakeshott, Steve, Kwan, Mei, Beltran, Jose, Ghavami, Afshin, Brunner, Dani, Park, Larry C., Ramboz, Sylvie, Howland, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527464/
https://www.ncbi.nlm.nih.gov/pubmed/23284626
http://dx.doi.org/10.1371/journal.pone.0049838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527464/
https://www.ncbi.nlm.nih.gov/pubmed/23284626
http://dx.doi.org/10.1371/journal.pone.0049838

Ejemplares similares