Targeting the Unfolded Protein Response in Glioblastoma Cells with the Fusion Protein EGF-SubA

Rapidly growing tumors require efficient means to allow them to adapt to fluctuating microenvironments consisting of hypoxia, nutrient deprivation, and acidosis. The unfolded protein response (UPR) represents a defense mechanism allowing cells to respond to these adverse conditions. The chaperone pr...

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Detalles Bibliográficos
Autores principales: Prabhu, Antony, Sarcar, Bhaswati, Kahali, Soumen, Shan, Yuan, Chinnaiyan, Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527517/
https://www.ncbi.nlm.nih.gov/pubmed/23284962
http://dx.doi.org/10.1371/journal.pone.0052265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527517/
https://www.ncbi.nlm.nih.gov/pubmed/23284962
http://dx.doi.org/10.1371/journal.pone.0052265

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