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Chimaerin Suppresses Rac1 Activation at the Apical Membrane to Maintain the Cyst Structure

Epithelial organs are made of a well-polarized monolayer of epithelial cells, and their morphology is maintained strictly for their proper functions. Previously, we showed that Rac1 activation is suppressed at the apical membrane in the mature organoid, and that such spatially biased Rac1 activity i...

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Detalles Bibliográficos
Autores principales: Yagi, Shunsuke, Matsuda, Michiyuki, Kiyokawa, Etsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527519/
https://www.ncbi.nlm.nih.gov/pubmed/23284959
http://dx.doi.org/10.1371/journal.pone.0052258