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Chimaerin Suppresses Rac1 Activation at the Apical Membrane to Maintain the Cyst Structure
Epithelial organs are made of a well-polarized monolayer of epithelial cells, and their morphology is maintained strictly for their proper functions. Previously, we showed that Rac1 activation is suppressed at the apical membrane in the mature organoid, and that such spatially biased Rac1 activity i...
Autores principales: | Yagi, Shunsuke, Matsuda, Michiyuki, Kiyokawa, Etsuko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527519/ https://www.ncbi.nlm.nih.gov/pubmed/23284959 http://dx.doi.org/10.1371/journal.pone.0052258 |
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