Vaccination with L. infantum chagasi Nucleosomal Histones Confers Protection against New World Cutaneous Leishmaniasis Caused by Leishmania braziliensis

BACKGROUND: Nucleosomal histones are intracellular proteins that are highly conserved among Leishmania species. After parasite destruction or spontaneous lysis, exposure to these proteins elicits a strong host immune response. In the present study, we analyzed the protective capability of Leishmania...

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Detalles Bibliográficos
Autores principales: Carneiro, Marcia W., Santos, Diego M., Fukutani, Kiyoshi F., Clarencio, Jorge, Miranda, Jose Carlos, Brodskyn, Claudia, Barral, Aldina, Barral-Netto, Manoel, Soto, Manuel, de Oliveira, Camila I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527524/
https://www.ncbi.nlm.nih.gov/pubmed/23284976
http://dx.doi.org/10.1371/journal.pone.0052296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527524/
https://www.ncbi.nlm.nih.gov/pubmed/23284976
http://dx.doi.org/10.1371/journal.pone.0052296

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