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Cdk2 Silencing via a DNA/PCL Electrospun Scaffold Suppresses Proliferation and Increases Death of Breast Cancer Cells

RNA interference (RNAi) is a promising approach for cancer treatment. Site specific and controlled delivery of RNAi could be beneficial to the patient, while at the same time reducing undesirable off-target side effects. We utilized electrospinning to generate a biodegradable scaffold capable of inc...

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Detalles Bibliográficos
Autores principales: Achille, Clément, Sundaresh, Sowmya, Chu, Benjamin, Hadjiargyrou, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527537/
https://www.ncbi.nlm.nih.gov/pubmed/23285007
http://dx.doi.org/10.1371/journal.pone.0052356