Solution Structure of the Oncogenic MIEN1 Protein Reveals a Thioredoxin-Like Fold with a Redox-Active Motif

The novel tumor biomarker MIEN1, identified by representational difference analysis, is overexpressed in breast cancer and prostate cancer. MIEN1 is considered an oncogenic protein, because MIEN1 overexpression functionally enhances migration and invasion of tumor cells via modulating the activity o...

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Detalles Bibliográficos
Autores principales: Hsu, Chun-Hua, Shen, Tang-Long, Chang, Chi-Fon, Chang, Yu-Yung, Huang, Lin-Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527542/
https://www.ncbi.nlm.nih.gov/pubmed/23284973
http://dx.doi.org/10.1371/journal.pone.0052292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527542/
https://www.ncbi.nlm.nih.gov/pubmed/23284973
http://dx.doi.org/10.1371/journal.pone.0052292

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