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N-glycosylation Dictates Proper Processing of Organic Anion Transporting Polypeptide 1B1

Organic anion transporting polypeptides (OATPs) have been extensively recognized as key determinants of absorption, distribution, metabolism and excretion (ADME) of various drugs, xenobiotics and toxins. Putative N-glycosylation sites located in the extracellular loops 2 and 5 is considered a common...

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Detalles Bibliográficos
Autores principales: Yao, Juan, Hong, Weifang, Huang, Jiujiu, Zhan, Kai, Huang, Hong, Hong, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527552/
https://www.ncbi.nlm.nih.gov/pubmed/23285087
http://dx.doi.org/10.1371/journal.pone.0052563