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miR-203 Regulates Cell Proliferation through Its Influence on Hakai Expression

Gene expression is potently regulated through the action of microRNAs (miRNAs). Here, we present evidence of a miRNA regulating Hakai protein. Hakai was discovered as an E3 ubiquitin-ligase that mediates the posttranslational downregulation of E-cadherin, a major component of adherens junctions in e...

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Detalles Bibliográficos
Autores principales: Abella, Vanessa, Valladares, Manuel, Rodriguez, Teresa, Haz, Mar, Blanco, Moisés, Tarrío, Nuria, Iglesias, Pilar, Aparicio, Luís A., Figueroa, Angélica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527564/
https://www.ncbi.nlm.nih.gov/pubmed/23285092
http://dx.doi.org/10.1371/journal.pone.0052568