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miR-203 Regulates Cell Proliferation through Its Influence on Hakai Expression
Gene expression is potently regulated through the action of microRNAs (miRNAs). Here, we present evidence of a miRNA regulating Hakai protein. Hakai was discovered as an E3 ubiquitin-ligase that mediates the posttranslational downregulation of E-cadherin, a major component of adherens junctions in e...
Autores principales: | Abella, Vanessa, Valladares, Manuel, Rodriguez, Teresa, Haz, Mar, Blanco, Moisés, Tarrío, Nuria, Iglesias, Pilar, Aparicio, Luís A., Figueroa, Angélica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527564/ https://www.ncbi.nlm.nih.gov/pubmed/23285092 http://dx.doi.org/10.1371/journal.pone.0052568 |
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