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A Subclone of HuH-7 with Enhanced Intracellular Hepatitis C Virus Production and Evasion of Virus Related-Cell Cycle Arrest

Hepatitis C virus (HCV) cell culture system with JFH-1 strain and HuH-7 cells enabled us to produce infectious HCV particles in vitro, and such system is useful to explore the anti-HCV compounds and to develop the vaccine against HCV. In the present study, we describe the derivation of a cell line t...

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Detalles Bibliográficos
Autores principales: Murayama, Asako, Sugiyama, Nao, Yoshimura, Seiko, Ishihara-Sugano, Mitsuko, Masaki, Takahiro, Kim, Sulyi, Wakita, Takaji, Mishiro, Shunji, Kato, Takanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527576/
https://www.ncbi.nlm.nih.gov/pubmed/23285155
http://dx.doi.org/10.1371/journal.pone.0052697