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Age-Related Changes in the Global DNA Methylation Profile of Leukocytes Are Linked to Nutrition but Are Not Associated with the MTHFR C677T Genotype or to Functional Capacities

Global DNA methylation of peripheral blood leukocytes has been recently proposed as a potential biomarker for disease risk. However, the amplitude of the changes in DNA methylation associated with normal aging and the impacts of environmental changes on this variation are still unclear. In this cont...

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Detalles Bibliográficos
Autores principales: Gomes, Marcus V. M., Toffoli, Leandro V., Arruda, Douglas W., Soldera, Larissa M., Pelosi, Gislaine G., Neves-Souza, Rejane D., Freitas, Eliane R., Castro, Denilson T., Marquez, Audrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527598/
https://www.ncbi.nlm.nih.gov/pubmed/23285094
http://dx.doi.org/10.1371/journal.pone.0052570