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Green Tea Polyphenols Induce p53-Dependent and p53-Independent Apoptosis in Prostate Cancer Cells through Two Distinct Mechanisms

Inactivation of the tumor suppressor gene p53 is commonly observed in human prostate cancer and is associated with therapeutic resistance. We have previously demonstrated that green tea polyphenols (GTP) induce apoptosis in prostate cancer cells irrespective of p53 status. However, the molecular mec...

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Detalles Bibliográficos
Autores principales: Gupta, Karishma, Thakur, Vijay S., Bhaskaran, Natarajan, Nawab, Akbar, Babcook, Melissa A., Jackson, Mark W., Gupta, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527608/
https://www.ncbi.nlm.nih.gov/pubmed/23285096
http://dx.doi.org/10.1371/journal.pone.0052572