CBP and p300 Histone Acetyltransferases Contribute to Homologous Recombination by Transcriptionally Activating the BRCA1 and RAD51 Genes

Histone acetylation at DNA double-strand break (DSB) sites by CBP and p300 histone acetyltransferases (HATs) is critical for the recruitment of DSB repair proteins to chromatin. Here, we show that CBP and p300 HATs also function in DSB repair by transcriptionally activating the BRCA1 and RAD51 genes...

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Detalles Bibliográficos
Autores principales: Ogiwara, Hideaki, Kohno, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527616/
https://www.ncbi.nlm.nih.gov/pubmed/23285190
http://dx.doi.org/10.1371/journal.pone.0052810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527616/
https://www.ncbi.nlm.nih.gov/pubmed/23285190
http://dx.doi.org/10.1371/journal.pone.0052810

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