Kinetic properties and small-molecule inhibition of human myosin-6

Myosin-6 is an actin-based motor protein that moves its cargo towards the minus-end of actin filaments. Mutations in the gene encoding the myosin-6 heavy chain and changes in the cellular abundance of the protein have been linked to hypertrophic cardiomyopathy, neurodegenerative diseases, and cancer...

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Detalles Bibliográficos
Autores principales: Heissler, Sarah M., Selvadurai, Jayashankar, Bond, Lisa M., Fedorov, Roman, Kendrick-Jones, John, Buss, Folma, Manstein, Dietmar J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527664/
https://www.ncbi.nlm.nih.gov/pubmed/22884421
http://dx.doi.org/10.1016/j.febslet.2012.07.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527664/
https://www.ncbi.nlm.nih.gov/pubmed/22884421
http://dx.doi.org/10.1016/j.febslet.2012.07.014

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