The C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stability

BACKGROUND: Bloom syndrome is a rare cancer-prone disorder in which the cells of affected persons have a high frequency of somatic mutation and genomic instability. Bloom syndrome cells have a distinctive high frequency of sister chromatid exchange and quadriradial formation. BLM, the protein altere...

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Detalles Bibliográficos
Autores principales: Yankiwski, Victor, Noonan, James P, Neff, Norma F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC35277/
https://www.ncbi.nlm.nih.gov/pubmed/11472631
http://dx.doi.org/10.1186/1471-2121-2-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC35277/
https://www.ncbi.nlm.nih.gov/pubmed/11472631
http://dx.doi.org/10.1186/1471-2121-2-11

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