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The C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stability
BACKGROUND: Bloom syndrome is a rare cancer-prone disorder in which the cells of affected persons have a high frequency of somatic mutation and genomic instability. Bloom syndrome cells have a distinctive high frequency of sister chromatid exchange and quadriradial formation. BLM, the protein altere...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC35277/ https://www.ncbi.nlm.nih.gov/pubmed/11472631 http://dx.doi.org/10.1186/1471-2121-2-11 |