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The Utility of Mitochondrial and Y Chromosome Phylogenetic Data to Improve Correction for Population Stratification

Genome-wide association (GWA) studies have become a standard approach for discovering and validating genomic polymorphisms putatively associated with phenotypes of interest. Accounting for population structure in GWA studies is critical to attain unbiased parameter measurements and control Type I er...

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Detalles Bibliográficos
Autores principales: Makowsky, Robert, Yan, Qi, Wiener, Howard W., Sandel, Michael, Aissani, Brahim, Tiwari, Hemant K., Shrestha, Sadeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527715/
https://www.ncbi.nlm.nih.gov/pubmed/23267368
http://dx.doi.org/10.3389/fgene.2012.00301