Peripheral injections of melanin-concentrating hormone receptor 1 antagonist S38151 decrease food intake and body weight in rodent obesity models

The compound S38151 is a nanomolar antagonist that acts at the melanin-concentrating hormone receptor 1 (MCH(1)). S38151 is more stable than its purely peptide counterpart, essentially because of the blockade of its N-terminus. Therefore, its action on various models of obesity was studied. Acute in...

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Detalles Bibliográficos
Autores principales: Della-Zuana, Odile, Audinot, Valérie, Levenez, Viviane, Ktorza, Alain, Presse, Françoise, Nahon, Jean-Louis, Boutin, Jean A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527734/
https://www.ncbi.nlm.nih.gov/pubmed/23267345
http://dx.doi.org/10.3389/fendo.2012.00160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527734/
https://www.ncbi.nlm.nih.gov/pubmed/23267345
http://dx.doi.org/10.3389/fendo.2012.00160

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