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RSK2 Protein Suppresses Integrin Activation and Fibronectin Matrix Assembly and Promotes Cell Migration

Modulation of integrin activation is important in many cellular functions including adhesion, migration, and assembly of the extracellular matrix. RSK2 functions downstream of Ras/Raf and promotes tumor cell motility and metastasis. We therefore investigated whether RSK2 affects integrin function. W...

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Detalles Bibliográficos
Autores principales: Gawecka, Joanna E., Young-Robbins, Shirley S., Sulzmaier, Florian J., Caliva, Maisel J., Heikkilä, Minna M., Matter, Michelle L., Ramos, Joe W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527930/
https://www.ncbi.nlm.nih.gov/pubmed/23118220
http://dx.doi.org/10.1074/jbc.M112.423046